Please cite LEVER using either or both of
* M. Winter, W. Mankowski, E. Wait, S. Temple and A. R. Cohen, LEVER: software tools for segmentation, tracking and lineaging of proliferating cells, Bioinformatics. 2016, (pdf) doi:10.1093/bioinformatics/btw406.
* M. Winter, M. Liu, D. Monteleone, J. Melunis, U. Hershberg, S. K. Goderie, S. Temple and A. R. Cohen, Computational Image Analysis Reveals Intrinsic Multigenerational Differences Between Anterior and Posterior Cerebral Cortex Neural Progenitor Cells, Stem Cell Reports, 2015, http://www.ncbi.nlm.nih.gov/pubmed/26344906.
Additional LEVER publications include:
* M. Winter, E. Wait, B. Roysam, S. Goderie, E. Kokovay, S. Temple and A. R. Cohen, Vertebrate neural stem cell segmentation, tracking and lineaging with validation and editing, Nature Protocols, vol. 6, pp. 1942-1952, 2011, http://www.ncbi.nlm.nih.gov/pubmed/25571242.
* W. C. Mankowski, M. R. Winter, E. Wait, M. Lodder, T. Schumacher, S. H. Naik and A. R. Cohen, Segmentation of occluded hematopoietic stem cells from tracking, IEEE Engineering in Medicine and Biology Society (EMBS) Conference, vol. 2014, pp. 5510-3, 2014, http://www.ncbi.nlm.nih.gov/pubmed/25571242.
* E. Wait, M. Winter, C. Bjornsson, E. Kokovay, Y. Wang, S. Goderie, S. Temple and A. R. Cohen, Visualization and correction of automated segmentation, tracking and lineaging from 5-D stem cell image sequences, BMC Bioinformatics, vol. 15, 2014, http://www.ncbi.nlm.nih.gov/pubmed/25281197.
LEVER uses an integrated tracking algorithm called Multitemporal Association Tracking (MAT). The algorithm, applied to tracking axonal organelle transport was originally published in the International Journal of Computational Biology and Drug Design. This is the best reference on MAT. A comparison of MAT and other particle tracking algorithms was subsequently published in Nature Methods. The same MAT algorithm, consisting of just a few hundred lines of C code has been applied to dozens of applications in cell and organelle tracking.
* Winter, M., C. Fang, G. Banker, B. Roysam, and A. R. Cohen, Axonal transport analysis using Multitemporal Association Tracking, International Journal of Computational Biology and Drug Design, vol. 5, pp. 35-48, 2012, http://www.ncbi.nlm.nih.gov/pubmed/22436297.
* Chenouard et al., Objective comparison of particle tracking methods, Nature Methods, Jan 19 2014, http://www.ncbi.nlm.nih.gov/pubmed/24441936.